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ELECTROPHYSIOLOGY

Co-Coordinators

Skaliora Ι, Research Assistant Professor of Neuroscience

Consoulas C. Associate Professor of Physiology

Teaching hours and weekly schedule

This a 2 weeks course that corresponds to 3 ECTs and 36 total hours of teaching; 21 hours lectures and 15 hours of student presentation. Your proposal includes 20 hours lectures and 16 hours of student presentation.

The course will take place in March-April-May-June (will be defined according to the selection of courses by the students) and the weekly schedule could be according to the table below. The teaching hours/day may be increased if necessary

Weekly Program for 3 ECTs

3 ECTs=21 hours of teaching+15 hours student presentations

Total: 2 weeks Χ teaching hours/day

Monday

4

8

Tuesday

4

8

Wednesday

4

8

Thursday

4

8

Friday

4

4

 

 

36

Description:

This two-week course will focus on cellular and molecular neuroscience. It will cover the mechanisms that operate to regulate neuronal excitability, dendritic and synaptic function; plasticity and neural circuits.  This is an intensive course focused on cellular neurophysiology. The main aim of the course is to understand the principles of signal generation, modulation and transmission, both at the cell and circuit level. The goal of this course is to enable

Learning Resource

Kandel ER, Schwartz JH, Jessell, TM, et al. Principles of Neural Science 5th Edition (2012). McGraw-Hill NY. ISBN 0071390111

Course Overview

•             Introduction lecture

•             Ion channels

•             Membrane potential, Nernst Equation, Goldman Equation

•             Electrotonic potential

•             Passive membrane properties

•             Action potential

•             Na+, K+, and Ca++ channels and currents

•             Mechanisms of pre-synaptic release

•             Synaptic transmission - ligand gated and G-protein synaptic transmission

•             Neuromuscular Junction

•             CNS synaptic transmission 1- excitation Glutamatergic

•             CNS synaptic transmission 2- inhibition - GABAergic and Glycinergic

•             CNS synaptic transmission 3- synaptic integration.

•             Neural Circuits: methods of recording and analysis

•             Modulation of Neural Circuits

 

Titles of the lectures and the names of the lecturers

 

A/A

Lecture Hours

Cellular neurophysiology

Lecturer

 

 

 

 

1

3

Basis of excitability, resting potential

Irini Skaliora

2

3

Passive and active properties (Action potential,  τ,  cable theory)

Christos Consoulas

3

3

Synapses (NMJ and central) signal integration and processing

Christos Consoulas

4

3

Synaptic modulation, neurotransmitter and receptors

Cornelia Poulopoulou

5

3

Recording techniques

Elias Koutsoukos

6

3

Dendritic recordings Ca imaging

Carsten Duch

7

3

Network analysis

Irini Skaliora

 

Total Lecture hours

21

 

 

Total student presentation hours

15

 

 

Total teaching hours

36