To see the program of lectures for the Academich year 2022-2023 Please, click here.
Dimitra Mangoura, Professor-Investigator A, Biomedical Research Foundation of the Academy of Athens
Zafiroula–Iro Georgoussi, Research Director, National Center for Scientific Research “Demokritos”, Athens
This is a 1st semester 3 weeks obligatory course that corresponds to 5.5 ECTs and 50 total hours of lectures and student presentations.
Description
This course is designed to introduce graduate students to major processes, principles, and mechanisms associated with Cellular and Molecular Neurobiology. Therefore the material will range from the mechanistic details of neuronal signaling and cellular function to how such properties utilized during normal brain function and neuropathology or substance abuse. The Course involves a series of overview lectures by leading researchers in the field, a total of fifteen Instructors from Greece and across Europe, and opportunities of presenting primary research or literature review papers by students.
More specifically, this Course will include the following major topics: overview of the neuron as the fundamental unit; cell biology of neurons and glia; ion channels and electrical signaling; synaptic transmission, integration, and chemical systems of the brain; molecular properties of neurotransmitters and their receptors; and sensory systems, from transduction to perception. Students will emerge with a great awareness of how individual nerve cells function, and neurons communicate with other cells, and of the ways that neurotransmission can provide insight into basic scientific questions, all in preparation for students own contributions as neuroscientists and biologists.
This is a comprehensive introductory course in Molecular and Cellular Neuroscience. Basic principles of organization and function of the nervous system will be discussed and frequent reference will be made to pathophysiology of neurological and other disorders.
• General principles of Nervous System
• Synaptic Transmission, Neurotransmitters and their Receptors
• Molecular Aspects of Neuronal Cells
Upon successful completion of this course, students will be able to know the fundamental principles on:
Cellular and Molecular Neuroscience | Lecturers |
Co-ordinators: Dimitra Mangoura, Zafeiroula-Iro Georgoussi | |
Cellular and Molecular Neurobiology | |
Overview of the Nervous System | Mimika Mangoura |
Cell Membrane Structures and Functions | Mimika Mangoura |
The cytoskeleton of neural cells | Mimika Mangoura |
Intracellular Trafficking | Mimika Mangoura |
Axonal transport | Mimika Mangoura |
Protein synthesis and posttranslational modifications | Mimika Mangoura |
Passive/active properties (Action potential, cable theory) | Christos Consoulas |
Synapses (NMJ, central), signal integration | Christos Consoulas |
Basis of excitability, resting potential | Irene Skaliora |
Cellular Plasticity, LTP/LTD | Irene Skaliora |
Synaptic Transmission and Signalling | |
Neurotransmitters, Receptors, G proteins | Iro Georgoussi |
Effectors, signaling intermediates, drug design | Iro Georgoussi |
Neurobiology of addiction | Katia Befort, France |
Neurotransmitters II: Gas neurotransmitters | Spiros Efthimiopoulos |
Neurotransmitters I: Cannabinoid receptors | Ismael Galve-Roperh, Spain |
Brain energy | Juan Pedro Bolaños, Spain |
Phosphoinositides | George Leondaritis |
Neurotransmitters III: GABA | Haralambos Lambrakakis |
Neurotransmitters V: Peptide neurotransmitters | Iro Georgoussi |
Neurotransmitters IV: Acetylcholine | Marios Zouridakis |
Neurotransmitters V: Glutamate | Costas Vekrellis |
Neurotransmitters VI: Catecholamines | Costas Vekrellis |
Ca2+ signaling and Homeostasis | Panagiota Papazafiri |